Guillain-Barre syndrome and Campylobacter jejuni: a serological study.
نویسندگان
چکیده
منابع مشابه
Campylobacter jejuni infection and Guillain-Barré syndrome.
BACKGROUND Although infection with Campylobacter jejuni is recognized as a common antecedent of the Guillain-Barré syndrome, the clinical and epidemiologic features of this association are not well understood. METHODS We performed a prospective case-control study in a cohort of patients with Guillain-Barré syndrome (96 patients) or Miller Fisher syndrome (7 patients) who were admitted to hosp...
متن کاملGuillain--Barré syndrome and Campylobacter jejuni infection.
1. SUMMARY Guillain±Barre  syndrome (GBS) is the most common cause of acute neuromuscular paralysis, usually due to acute in¯ammatory demyelinating polyradiculoneuropathy. The presence of activated T lymphocytes and antibodies against peripheral nerve myelin suggests an autoimmune patho-genesis, although there is wide heterogeneity. Gangliosides are sialylated glycolipids widely distributed in...
متن کاملCampylobacter jejuni - mediated Guillain - Barre Syndrome , an overview of the molecular mimicry and vaccine development approaches
Guillain-Barre syndrome (GBS) is an autoimmune disease in which body’s immune system attacks the nervous system that leads to nerve inflammation causing muscle weakness. This syndrome affects people of both sexes between ages 25 and 50 years. It is not clear what exactly triggers GBS. However, Campylobacter jejuni is found to be the most common pathogenic factor that is found to trigger GBS and...
متن کاملCarbohydrate mimicry between human ganglioside GM1 and Campylobacter jejuni lipooligosaccharide causes Guillain-Barre syndrome.
Molecular mimicry between microbial and self-components is postulated as the mechanism that accounts for the antigen and tissue specificity of immune responses in postinfectious autoimmune diseases. Little direct evidence exists, and research in this area has focused principally on T cell-mediated, antipeptide responses, rather than on humoral responses to carbohydrate structures. Guillain-Barr...
متن کاملGuillain-Barre’ Syndrome: A Case Report
Background and Objectives: Guillain-Barre´ Syndrome (GBS) is an acute-onset, monophasic, immune-mediated polyneuropathy that often follows an antecedent infection. Special nutritional support has an important role in these patients. Methods: A 6 years old girl with GBS was admitted to PICU of Dr. Sheikh Children Hospital (Mashhad, Iran). Chief compliance for hospitalization was inability to w...
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ژورنال
عنوان ژورنال: BMJ
سال: 1984
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.288.6434.1867